ADAM2

GENE INFORMATION

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Gene name

ADAM2 (HGNC Symbol)

Synonyms

CT15, FTNB, PH-30b, PH30

Description

ADAM metallopeptidase domain 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]

Chromosome

8 (Chromosome progress)

Cytoband

p11.22

Chromosome location (bp)

39601254 - 39695808

Ensembl

ENSG00000104755 (version 73.37)

Entrez gene

2515

UniProt

Q99965 (UniProt - Evidence at protein level)

neXtProt

NX_Q99965

Antibodypedia

ADAM2 antibodies
 

PROTEIN VIEW

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ADAM2-001
 
ADAM2-002
 
ADAM2-003
 
ADAM2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM2-001 ENSP00000265708
ENST00000265708
Q99965
Show all »
Show » Show » 735 82.5 Yes 1
ADAM2-002 ENSP00000429352
ENST00000521880
B4DWY7
Show all »
Show » Show » 672 75.6 Yes 1
ADAM2-003 ENSP00000343854
ENST00000347580
Q99965
Show all »
Show » Show » 716 80.2 Yes 1
ADAM2-004 ENSP00000369182
ENST00000379853
Q6P2G0
Show all »
Show » Show » 579 64.8 Yes 1