Fields »

SUBCELLULAR LOCATION

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Main location(s)

Mitochondria

Additional location(s)

Nucleus but not nucleoli 

Staining summary

Mainly localized to the mitochondria. In addition localized to the nucleus.

Reliability (APE)

Medium

Antibodies in assay

HPA015652, CAB025371
 

Antibody HPA015652

 

Antibody CAB025371

 

         Cell line A-431

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Location(s)

Nucleus but not nucleoli, Mitochondria Mitochondria 

Staining characteristics

  

Staining intensity

Moderate Weak 

Validation

Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Nucleus but not nucleoli, Mitochondria Mitochondria 

Staining characteristics

Speckle  

Staining intensity

Moderate Weak 

Validation

Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
 
One/multiple location(s) with no available experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Nucleus but not nucleoli, Mitochondria   

Staining characteristics

Speckle   

Staining intensity

Moderate   

Validation

Not decisive - One/multiple location(s) where experimental gene/protein characterization data is partly supporting and partly conflicting.
   

Comment

   

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli & mitochondria.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in mitochondria.
 

Summary

Speckled staining of nucleus and mitochondria in all three cell lines.   Staining of mitochondria in A-431 and U-2 OS.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Mitochondria
Nucleus but not nucleoli