KCNA7

GENE INFORMATION

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Gene name

KCNA7 (HGNC Symbol)

Synonyms

HAK6, Kv1.7

Description

potassium voltage-gated channel, shaker-related subfamily, member 7 (HGNC Symbol)

Entrez gene summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

49570675 - 49576198

Ensembl

ENSG00000104848 (version 73.37)

Entrez gene

3743

UniProt

Q96RP8 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96RP8

Antibodypedia

KCNA7 antibodies
 

PROTEIN VIEW

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KCNA7-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNA7-001 ENSP00000221444
ENST00000221444
Q96RP8
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