VRK3

GENE INFORMATION

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Gene name

VRK3

Synonyms

Description

Vaccinia related kinase 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49976467 - 50025946

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105053 (version 78.38)

Entrez gene

51231

UniProt

Q8IV63 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IV63

Antibodypedia

VRK3 antibodies
 

PROTEIN VIEW

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 « 
 
VRK3-001
 
VRK3-002
 
VRK3-004
 
VRK3-005
 
VRK3-006
 
VRK3-007
 
VRK3-008
 
VRK3-009
 
VRK3-014
 
VRK3-016
 
VRK3-017
 
VRK3-019
 
VRK3-021
 
VRK3-022
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VRK3-001 ENSP00000324636
ENST00000316763
Q8IV63
Show all »
Show » Show » 474 52.9 No 0
VRK3-002 ENSP00000366210
ENST00000377011
Q8IV63
Show all »
Show » Show » 424 47.5 No 0
VRK3-004 ENSP00000472541
ENST00000594092
Q8IV63
Show all »
Show » Show » 412 45.9 No 0
VRK3-005 ENSP00000471061
ENST00000601912
M0R073
Show all »
Show » Show » 362 40.5 No 0
VRK3-006 ENSP00000470156
ENST00000601341
Q8IV63
Show all »
Show » Show » 424 47.5 No 0
VRK3-007 ENSP00000473171
ENST00000594948
Q8IV63
Show all »
Show » Show » 474 52.9 No 0
VRK3-008 ENSP00000469710
ENST00000593919
M0QYA8
Show all »
Show » Show » 406 45.2 No 0
VRK3-009 ENSP00000469880
ENST00000599538
Q8IV63
Show all »
Show » Show » 474 52.9 No 0
VRK3-014 ENSP00000470359
ENST00000601324
M0QZ79
Show all »
Show » 112 12 No 0
VRK3-016 ENSP00000468979
ENST00000600137
M0QX88
Show all »
Show » 178 19.5 No 0
VRK3-017 ENSP00000470940
ENST00000597215
M0R025
Show all »
Show » 182 19.9 No 0
VRK3-019 ENSP00000469400
ENST00000600259
M0QXV1
Show all »
Show » 150 16.4 No 0
VRK3-021 ENSP00000473222
ENST00000593912
M0R3H2
Show all »
Show » Show » 117 13.2 No 0
VRK3-022 ENSP00000469092
ENST00000596445
M0QXD7
Show all »
Show » 169 18.3 No 0