AURKC

GENE INFORMATION

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Gene name

AURKC (HGNC Symbol)

Synonyms

ARK3, AurC, STK13

Description

aurora kinase C (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.43

Chromosome location (bp)

57742377 - 57746916

Ensembl

ENSG00000105146 (version 73.37)

Entrez gene

6795

UniProt

Q9UQB9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UQB9

Antibodypedia

AURKC antibodies
 

PROTEIN VIEW

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AURKC-001
 
AURKC-002
 
AURKC-003
 
AURKC-004
 
AURKC-005
 
AURKC-006
 
AURKC-007
 
AURKC-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AURKC-001 ENSP00000302898
ENST00000302804
Q9UQB9
Show all »
Show » Show » 309 35.6 No 0
AURKC-002 ENSP00000407162
ENST00000415300
Q9UQB9
Show all »
Show » Show » 290 33.7 No 0
AURKC-003 ENSP00000469983
ENST00000599062
Q5Y191
Show all »
Show » Show » 306 35.3 No 0
AURKC-004 ENSP00000471830
ENST00000598785
Q9UQB9
Show all »
Show » Show » 275 32.2 No 0
AURKC-005 ENSP00000469894
ENST00000594599
M0QYK8
Show all »
Show » Show » 137 16 No 0
AURKC-006 ENSP00000470465
ENST00000596375
B4DXA6
Show all »
Show » 113 13.5 No 0
AURKC-007 ENSP00000468918
ENST00000601799
M0QX60
Show all »
46 5.1 No 0
AURKC-201 ENSP00000406798
ENST00000448930
Q9UQB9
Show all »
Show » Show » 275 32.2 No 0