PRX

GENE INFORMATION

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Gene name

PRX (HGNC Symbol)

Synonyms

KIAA1620

Description

periaxin (HGNC Symbol)

Entrez gene summary

This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

40899675 - 40919273

Ensembl

ENSG00000105227 (version 73.37)

Entrez gene

57716

UniProt

Q9BXM0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BXM0

Antibodypedia

PRX antibodies
 

PROTEIN VIEW

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PRX-001
 
PRX-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRX-001 ENSP00000326018
ENST00000324001
Q9BXM0
Show all »
Show » 1461 154.9 No 0
PRX-002 ENSP00000291825
ENST00000291825
Q9BXM0
Show all »
Show » 147 15.9 No 0