MRPL4

GENE INFORMATION

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Gene name

MRPL4 (HGNC Symbol)

Synonyms

CGI-28

Description

mitochondrial ribosomal protein L4 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified alternatively spliced variants that encode different protein isoforms. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

10362577 - 10370721

Ensembl

ENSG00000105364 (version 73.37)

Entrez gene

51073

UniProt

Q9BYD3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BYD3

Antibodypedia

MRPL4 antibodies
 

PROTEIN VIEW

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MRPL4-001
 
MRPL4-002
 
MRPL4-003
 
MRPL4-006
 
MRPL4-007
 
MRPL4-008
 
MRPL4-009
 
MRPL4-010
 
MRPL4-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL4-001 ENSP00000253099
ENST00000253099
Q9BYD3
Show all »
Show » Show » 311 34.9 No 0
MRPL4-002 ENSP00000465143
ENST00000590669
Q9BYD3
Show all »
Show » Show » 263 29.5 No 0
MRPL4-003 ENSP00000377334
ENST00000393733
K7EJ73
Show all »
Show » 357 39.6 No 0
MRPL4-006 ENSP00000468569
ENST00000592514
K7ES61
Show all »
Show » 300 33.8 No 0
MRPL4-007 ENSP00000465635
ENST00000591054
K7EKI4
Show all »
Show » 127 14.1 No 0
MRPL4-008 ENSP00000465050
ENST00000590702
K7EJ73
Show all »
Show » 119 13.4 No 0
MRPL4-009 ENSP00000466050
ENST00000590150
K7ELF1
Show all »
Show » 163 18 No 0
MRPL4-010 ENSP00000466169
ENST00000588502
K7ELQ0
Show all »
Show » 220 24.4 No 0
MRPL4-201 ENSP00000306902
ENST00000307422
Q9BYD3
Show all »
Show » Show » 311 34.9 No 0