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GENE INFORMATION

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Gene name

LIG1

Synonyms

Description

ligase I, DNA, ATP-dependent (HGNC Symbol)

Entrez gene summary

LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

48618703 - 48673601

Ensembl

ENSG00000105486 (version 69.37)

Entrez gene

3978

UniProt

P18858

neXtProt

NX_P18858

Antibodypedia

LIG1 antibodies
 

PROTEIN VIEW

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LIG1-201
 
LIG1-202
 
LIG1-203
 
LIG1-204
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LIG1-201 ENSP00000263274
ENST00000263274
P18858
Show all »
Show » Show » 919 101.7 No 0
LIG1-202 ENSP00000442841
ENST00000427526
B4DTU4
Show all »
Show » 888 98.2 No 0
LIG1-203 ENSP00000441531
ENST00000536218
F5GZ28
Show all »
Show » 851 93.9 No 0
LIG1-204 ENSP00000445928
ENST00000542460
B4E135
Show all »
Show » 415 45 No 0