PIK3R2

GENE INFORMATION

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Gene name

PIK3R2 (HGNC Symbol)

Synonyms

p85, P85B

Description

phosphoinositide-3-kinase, regulatory subunit 2 (beta) (HGNC Symbol)

Entrez gene summary

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2012]

Chromosome

19 (Chromosome progress)

Cytoband

p13.11

Chromosome location (bp)

18263626 - 18281350

Ensembl

ENSG00000105647 (version 73.37)

Entrez gene

5296

UniProt

O00459 (UniProt - Evidence at protein level)

neXtProt

NX_O00459

Antibodypedia

PIK3R2 antibodies
 

PROTEIN VIEW

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PIK3R2-001
 
PIK3R2-002
 
PIK3R2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIK3R2-001 ENSP00000222254
ENST00000222254
O00459
Show all »
Show » Show » 728 81.5 No 0
PIK3R2-002 ENSP00000395636
ENST00000426902
E9PFP1
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Show » Show » 481 52.7 No 0
PIK3R2-003 ENSP00000470075
ENST00000473973
M0QYU3
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Show » Show » 40 4.5 No 0