ATP4A

GENE INFORMATION

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Gene name

ATP4A (HGNC Symbol)

Synonyms

ATP6A

Description

ATPase, H+/K+ exchanging, alpha polypeptide (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.12

Chromosome location (bp)

36040945 - 36054560

Ensembl

ENSG00000105675 (version 73.37)

Entrez gene

495

UniProt

P20648 (UniProt - Evidence at transcript level)

neXtProt

NX_P20648

Antibodypedia

ATP4A antibodies
 

PROTEIN VIEW

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ATP4A-001
 
ATP4A-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP4A-001 ENSP00000262623
ENST00000262623
P20648
Show all »
Show » Show » 1035 114.1 No >9
ATP4A-004 ENSP00000472323
ENST00000592767
34 3.6 No 0