LMBR1

GENE INFORMATION

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Gene name

LMBR1 (HGNC Symbol)

Synonyms

ACHP, C7orf2, FLJ11665

Description

limb region 1 homolog (mouse) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q36.3

Chromosome location (bp)

156473571 - 156685924

Ensembl

ENSG00000105983 (version 73.37)

Entrez gene

64327

UniProt

Q8WVP7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WVP7

Antibodypedia

LMBR1 antibodies
 

PROTEIN VIEW

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LMBR1-001
 
LMBR1-002
 
LMBR1-003
 
LMBR1-004
 
LMBR1-005
 
LMBR1-009
 
LMBR1-010
 
LMBR1-013
 
LMBR1-014
 
LMBR1-201
 
LMBR1-202
 
LMBR1-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LMBR1-001 ENSP00000326604
ENST00000353442
Q8WVP7
Show all »
Show » Show » 490 55.1 No 9
LMBR1-002 ENSP00000397698
ENST00000434453
F8WB14
Show all »
Show » 48 5.7 No 1
LMBR1-003 ENSP00000414795
ENST00000454132
F8WDW0
Show all »
Show » 52 6.1 No 1
LMBR1-004 ENSP00000408256
ENST00000415428
H0Y6V6
Show all »
Show » 529 59.2 No 9
LMBR1-005 ENSP00000403052
ENST00000448926
H7C1Y4
Show all »
Show » Show » 45 5.1 No 1
LMBR1-009 ENSP00000413539
ENST00000434278
F8WEK4
Show all »
47 5.5 No 0
LMBR1-010 ENSP00000392557
ENST00000414218
F8WCL1
Show all »
38 4.5 No 0
LMBR1-013 ENSP00000393928
ENST00000444719
F8WEN8
Show all »
Show » Show » 63 7.6 No 1
LMBR1-014 ENSP00000395754
ENST00000434503
F2Z2Z3
Show all »
Show » 77 8.8 No 1
LMBR1-201 ENSP00000346500
ENST00000354505
Q8WVP7
Show all »
Show » Show » 531 59.5 No 9
LMBR1-202 ENSP00000352392
ENST00000359422
Q8NDP7
Show all »
Show » 284 31.5 Yes 4
LMBR1-203 ENSP00000445509
ENST00000540390
B7Z633
Show all »
Show » 415 45.7 No 7