GRB10

GENE INFORMATION

? »

Gene name

GRB10

Synonyms

Description

growth factor receptor-bound protein 10 (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]

Chromosome

7 (Chromosome progress)

Cytoband

p12.1

Chromosome location (bp)

50657760 - 50861159

Ensembl

ENSG00000106070 (version 73.37)

Entrez gene

2887

UniProt

Q13322 (UniProt - Evidence at protein level)

neXtProt

NX_Q13322

Antibodypedia

GRB10 antibodies
 

PROTEIN VIEW

? »
 
 
 « 
 
GRB10-001
 
GRB10-002
 
GRB10-003
 
GRB10-004
 
GRB10-005
 
GRB10-006
 
GRB10-007
 
GRB10-014
 
GRB10-015
 
GRB10-201
 
GRB10-202
 
GRB10-203
 
GRB10-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GRB10-001 ENSP00000385544
ENST00000403097
Q13322
Show all »
Show » Show » 588 66.5 No 0
GRB10-002 ENSP00000385748
ENST00000402497
Q13322
Show all »
Show » Show » 536 60.8 No 0
GRB10-003 ENSP00000385770
ENST00000401949
Q13322
Show all »
Show » Show » 594 67.2 No 0
GRB10-004 ENSP00000385366
ENST00000406641
Q13322
Show all »
Show » Show » 536 60.8 No 0
GRB10-005 ENSP00000349818
ENST00000357271
Q13322
Show all »
Show » Show » 548 62 No 0
GRB10-006 ENSP00000385189
ENST00000402578
Q13322
Show all »
Show » Show » 536 60.8 No 0
GRB10-007 ENSP00000385046
ENST00000407526
Q13322
Show all »
Show » Show » 536 60.8 No 0
GRB10-014 ENSP00000413023
ENST00000439044
C9JTW6
Show all »
114 12.4 No 0
GRB10-015 ENSP00000410920
ENST00000428711
H7C3B9
Show all »
Show » 108 12.7 No 0
GRB10-201 ENSP00000338543
ENST00000335866
Q13322
Show all »
Show » Show » 536 60.8 No 0
GRB10-202 ENSP00000381790
ENST00000398810
Q13322
Show all »
Show » Show » 536 60.8 No 0
GRB10-203 ENSP00000381793
ENST00000398812
Q13322
Show all »
Show » Show » 594 67.2 No 0
GRB10-204 ENSP00000406716
ENST00000439599
Q13322
Show all »
Show » Show » 588 66.5 No 0