CRHR2

GENE INFORMATION

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Gene name

CRHR2 (HGNC Symbol)

Synonyms

CRF-RB, CRF2, HM-CRF

Description

corticotropin releasing hormone receptor 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]

Chromosome

7 (Chromosome progress)

Cytoband

p14.3

Chromosome location (bp)

30692200 - 30739745

Ensembl

ENSG00000106113 (version 73.37)

Entrez gene

1395

UniProt

Q13324 (UniProt - Evidence at protein level)

neXtProt

NX_Q13324

Antibodypedia

CRHR2 antibodies
 

PROTEIN VIEW

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CRHR2-001
 
CRHR2-002
 
CRHR2-005
 
CRHR2-006
 
CRHR2-007
 
CRHR2-201
 
CRHR2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRHR2-001 ENSP00000340943
ENST00000348438
Q13324
Show all »
Show » Show » 438 50.8 Yes 7
CRHR2-002 ENSP00000418722
ENST00000471646
Q13324
Show all »
Show » Show » 411 47.7 No 7
CRHR2-005 ENSP00000401930
ENST00000452278
F2Z2M6
Show all »
Show » 64 7.1 Yes 0
CRHR2-006 ENSP00000401241
ENST00000445981
C9JZM9
Show all »
Show » 99 11 Yes 0
CRHR2-007 ENSP00000416620
ENST00000423776
F2Z2M6
Show all »
Show » 64 7.1 Yes 0
CRHR2-201 ENSP00000344304
ENST00000341843
Q13324
Show all »
Show » Show » 397 46.5 No 7
CRHR2-202 ENSP00000426498
ENST00000506074
F8WA81
Show all »
Show » Show » 370 42.8 No 7