EPHB6

GENE INFORMATION

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Gene name

EPHB6 (HGNC Symbol)

Synonyms

HEP

Description

EPH receptor B6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

7 (Chromosome progress)

Cytoband

q34

Chromosome location (bp)

142552792 - 142568847

Ensembl

ENSG00000106123 (version 73.37)

Entrez gene

2051

UniProt

O15197 (UniProt - Evidence at protein level)

neXtProt

NX_O15197

Antibodypedia

EPHB6 antibodies
 

PROTEIN VIEW

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EPHB6-001
 
EPHB6-003
 
EPHB6-004
 
EPHB6-201
 
EPHB6-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHB6-001 ENSP00000410789
ENST00000442129
O15197
Show all »
Show » Show » 1021 110.7 Yes 2
EPHB6-003 ENSP00000411175
ENST00000425995
F8WBX3
Show all »
Show » 50 5.1 Yes 0
EPHB6-004 ENSP00000404786
ENST00000422643
F8WCM8
Show all »
Show » Show » 183 20.6 Yes 0
EPHB6-201 ENSP00000376684
ENST00000392957
O15197
Show all »
Show » Show » 1021 110.7 Yes 2
EPHB6-202 ENSP00000409061
ENST00000411471
J3KQU5
Show all »
Show » Show » 744 81.2 No 1