ZKSCAN1

GENERAL INFORMATION

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Gene name

ZKSCAN1

Gene description

Zinc finger with KRAB and SCAN domains 1

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA006672
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ZKSCAN1 (HGNC Symbol)

Synonyms

KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33

Description

Zinc finger with KRAB and SCAN domains 1 (HGNC Symbol)

Entrez gene summary

The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

100015572 - 100041689

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106261 (version 78.38)

Entrez gene

7586

UniProt

P17029 (UniProt - Evidence at protein level)

neXtProt

NX_P17029

Antibodypedia

ZKSCAN1 antibodies


PROTEIN BROWSER

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ENST00000324306
 
ENST00000426572
 
ENST00000432317
 
ENST00000535170
 
ENST00000620510
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZKSCAN1-001 ENSP00000323148
ENST00000324306
P17029
Show all »
Show » Show » 563 63.6 No 0
ZKSCAN1-003 ENSP00000409172
ENST00000426572
E9PC66
Show all »
Show » Show » 527 59.7 No 0
ZKSCAN1-004 ENSP00000394445
ENST00000432317
C9JRM9
Show all »
Show » Show » 125 14.7 No 0
ZKSCAN1-201 ENSP00000443508
ENST00000535170
B3KRF7
Show all »
Show » Show » 350 39.3 No 0
ZKSCAN1-202 ENSP00000480305
ENST00000620510
E9PC66
Show all »
Show » Show » 527 59.7 No 0