SNX8

GENE INFORMATION

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Gene name

SNX8 (HGNC Symbol)

Synonyms

Mvp1

Description

Sorting nexin 8 (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

7

Cytoband

p22.3

Chromosome location (bp)

2291405 - 2393953

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106266 (version 75.37)

Entrez gene

102465503

UniProt

Q9Y5X2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5X2

Antibodypedia

SNX8 antibodies
 

PROTEIN VIEW

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SNX8-001
 
SNX8-002
 
SNX8-003
 
SNX8-004
 
SNX8-005
 
SNX8-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNX8-001 ENSP00000222990
ENST00000222990
Q9Y5X2
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Show » Show » 465 52.6 No 0
SNX8-002 ENSP00000406212
ENST00000435336
C9J8E6
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Show » Show » 160 18.6 No 0
SNX8-003 ENSP00000403608
ENST00000447136
C9JCB9
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Show » Show » 85 10.1 No 0
SNX8-004 ENSP00000392437
ENST00000435060
C9J271
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Show » Show » 224 25.8 No 0
SNX8-005 ENSP00000399127
ENST00000419693
C9IYC5
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Show » 42 4.9 No 0
SNX8-006 ENSP00000406954
ENST00000457286
C9J014
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Show » Show » 176 20.5 No 0