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GENE INFORMATION

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Gene name

TAF6 (HGNC Symbol)

Synonyms

MGC:8964, TAF2E, TAFII70, TAFII80, TAFII85

Description

TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa (HGNC Symbol)

Entrez gene summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

99704693 - 99717464

Ensembl

ENSG00000106290 (version 64.37)

Entrez gene

6878

UniProt

P49848

neXtProt

NX_P49848
 

PROTEIN VIEW

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 « 
 
TAF6-001
 
TAF6-002
 
TAF6-003
 
TAF6-004
 
TAF6-007
 
TAF6-008
 
TAF6-009
 
TAF6-010
 
TAF6-012
 
TAF6-013
 
TAF6-014
 
TAF6-016
 
TAF6-017
 
TAF6-018
 
TAF6-019
 
TAF6-020
 
TAF6-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TAF6-001 ENSP00000344537
ENST00000344095
P49848
Show all »
Show » Show » 677 72.7 No 0
TAF6-002 ENSP00000399982
ENST00000437822
P49848
Show all »
Show » Show » 714 77 No 0
TAF6-003 ENSP00000413614
ENST00000421980
C9JHQ8
Show all »
Show » 114 13.1 No 0
TAF6-004 ENSP00000389575
ENST00000453269
P49848
Show all »
Show » Show » 677 72.7 No 0
TAF6-007 ENSP00000416396
ENST00000452041
P49848
Show all »
Show » Show » 677 72.7 No 0
TAF6-008 ENSP00000390073
ENST00000449571
C9JIS2
Show all »
Show » 134 15.3 No 0
TAF6-009 ENSP00000406315
ENST00000451699
C9J7C4
Show all »
Show » 114 13.1 No 0
TAF6-010 ENSP00000410012
ENST00000440225
C9JFL8
Show all »
Show » 233 25.8 No 0
TAF6-012 ENSP00000427710
ENST00000460673
9 1.1 No 0
TAF6-013 ENSP00000390220
ENST00000417349
C9JHQ8
Show all »
Show » 76 8.6 No 0
TAF6-014 ENSP00000412346
ENST00000452438
C9J088
Show all »
Show » 156 17.7 No 0
TAF6-016 ENSP00000419760
ENST00000472509
P49848
Show all »
Show » Show » 734 78.9 No 0
TAF6-017 ENSP00000419555
ENST00000493322
C9JTY6
Show all »
Show » 255 28.3 No 0
TAF6-018 ENSP00000395627
ENST00000431404
14 1.6 No 0
TAF6-019 ENSP00000428639
ENST00000523306
E5RHA1
Show all »
Show » 141 15.9 No 0
TAF6-020 ENSP00000428071
ENST00000520135
E5RKA5
Show all »
Show » 114 13 No 0
TAF6-201 ENSP00000407980
ENST00000418432
601 64.2 No 0