PSMA2

GENE INFORMATION

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Gene name

PSMA2 (HGNC Symbol)

Synonyms

HC3, MU, PMSA2

Description

proteasome (prosome, macropain) subunit, alpha type, 2 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

p14.1

Chromosome location (bp)

42956460 - 42971822

Ensembl

ENSG00000106588 (version 73.37)

Entrez gene

5683

UniProt

P25787 (UniProt - Evidence at protein level)

neXtProt

NX_P25787

Antibodypedia

PSMA2 antibodies
 

PROTEIN VIEW

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PSMA2-001
 
PSMA2-002
 
PSMA2-005
 
PSMA2-006
 
PSMA2-007
 
PSMA2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMA2-001 ENSP00000223321
ENST00000223321
P25787
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Show » Show » 234 25.9 No 0
PSMA2-002 ENSP00000401954
ENST00000411875
F8WEG3
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22 2.5 No 0
PSMA2-005 ENSP00000410750
ENST00000436986
18 2 No 0
PSMA2-006 ENSP00000404858
ENST00000445517
C9JCK5
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Show » 164 18.6 No 0
PSMA2-007 ENSP00000414832
ENST00000457444
H7C402
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Show » 36 3.6 No 0
PSMA2-201 ENSP00000440009
ENST00000538645
Q6MZI6
Show all »
Show » 99 11.3 No 0