MRPL32

GENERAL INFORMATION

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Gene name

MRPL32

Gene description

Mitochondrial ribosomal protein L32

Protein class

Mitochondrial proteins
Predicted secreted proteins
Ribosomal proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Respiratory epithelia, gastrointestinal tract, breast, placental trophoblasts, epididymis, smooth muscle cells and fraction of neuronal cells displayed moderate to strong cytoplasmic positivity. Moderate to strong cytoplasmic and membranous staining was observed in endometrial glands and squamous epithelia. Remaining normal cells were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA048965
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MRPL32 (HGNC Symbol)

Synonyms

bMRP-59b, HSPC283, L32mt, MRP-L32

Description

Mitochondrial ribosomal protein L32 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p14.1

Chromosome location (bp)

42932200 - 42948958

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106591 (version 78.38)

Entrez gene

64983

UniProt

Q9BYC8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BYC8

Antibodypedia

MRPL32 antibodies


PROTEIN BROWSER

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ENST00000223324
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL32-001 ENSP00000223324
ENST00000223324
Q9BYC8
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