SEC61B

GENE INFORMATION

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Gene name

SEC61B

Synonyms

Description

Sec61 beta subunit (HGNC Symbol)

Entrez gene summary

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple polyadenylated sites for this transcript. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q22.33

Chromosome location (bp)

101984346 - 101992897

Ensembl

ENSG00000106803 (version 73.37)

Entrez gene

10952

UniProt

P60468 (UniProt - Evidence at protein level)

neXtProt

NX_P60468

Antibodypedia

SEC61B antibodies
 

PROTEIN VIEW

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SEC61B-001
 
SEC61B-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SEC61B-001 ENSP00000223641
ENST00000223641
P60468
Show all »
Show » Show » 96 10 No 1
SEC61B-002 ENSP00000474122
ENST00000498603
Show » 42 4.9 No 1