AK1

GENE INFORMATION

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Gene name

AK1

Synonyms

Description

adenylate kinase 1 (HGNC Symbol)

Entrez gene summary

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3). AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q34.11

Chromosome location (bp)

130628759 - 130640022

Ensembl

ENSG00000106992 (version 73.37)

Entrez gene

203

UniProt

P00568 (UniProt - Evidence at protein level)

neXtProt

NX_P00568

Antibodypedia

AK1 antibodies
 

PROTEIN VIEW

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AK1-008
 
AK1-009
 
AK1-010
 
AK1-011
 
AK1-013
 
AK1-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AK1-008 ENSP00000362271
ENST00000373176
P00568
Show all »
Show » Show » 194 21.6 No 0
AK1-009 ENSP00000223836
ENST00000223836
Q5T9B7
Show all »
Show » 210 23.4 No 0
AK1-010 ENSP00000362249
ENST00000373156
P00568
Show all »
Show » Show » 194 21.6 No 0
AK1-011 ENSP00000392314
ENST00000413016
Show » 135 15.4 No 0
AK1-013 ENSP00000448741
ENST00000550992
F8VRY5
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32 3.1 No 0
AK1-014 ENSP00000449130
ENST00000550143
H0YID2
Show all »
Show » 51 5.8 No 0