RLN2

GENERAL INFORMATION

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Gene name

RLN2

Gene description

Relaxin 2

Protein class

Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (fallopian tube)
GTEx:Group enriched (prostate, testis)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (fallopian tube)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (prostate, testis)

Organ

Expression



GENE INFORMATION

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Gene name

RLN2 (HGNC Symbol)

Synonyms

bA12D24.1.1, bA12D24.1.2, H2, RLXH2

Description

Relaxin 2 (HGNC Symbol)

Entrez gene summary

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The active form of the protein encoded by this gene consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Chromosome

9

Cytoband

p24.1

Chromosome location (bp)

5299868 - 5304969

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107014 (version 78.38)

Entrez gene

6019

UniProt

P04090 (UniProt - Evidence at protein level)

neXtProt

NX_P04090

Antibodypedia

RLN2 antibodies


PROTEIN BROWSER

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ENST00000381627
 
ENST00000416837
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RLN2-001 ENSP00000371040
ENST00000381627
P04090
Show all »
Show » Show » 185 21 Yes 0
RLN2-002 ENSP00000399616
ENST00000416837
Show » 68 7.2 No 0