DOCK8

CANCER ATLAS

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Gene description

Dedicator of cytokinesis 8

Protein class

Disease related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Cervical cancer

STAINING SUMMARY

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HPA003218
 

Tissue

Cancer staining

Normal tissue
staining

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Normal tissue
staining

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Most malignant cells were weakly stained or negative. Moderate nuclear and cytoplasmic positivity was observed several cases of malignant melanoma, ovarian, cervical and urothelial cancers.
 

Level of antibody staining/expression





High
Medium
Low
Not detected