KCNT1

GENE INFORMATION

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Gene name

KCNT1 (HGNC Symbol)

Synonyms

KCa4.1, KIAA1422

Description

potassium channel, subfamily T, member 1 (HGNC Symbol)

Entrez gene summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Chromosome

9 (Chromosome progress)

Cytoband

q34.3

Chromosome location (bp)

138594031 - 138684992

Ensembl

ENSG00000107147 (version 73.37)

Entrez gene

57582

UniProt

Q5JUK3 (UniProt - Evidence at protein level)

neXtProt

NX_Q5JUK3

Antibodypedia

KCNT1 antibodies
 

PROTEIN VIEW

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KCNT1-001
 
KCNT1-002
 
KCNT1-003
 
KCNT1-004
 
KCNT1-005
 
KCNT1-006
 
KCNT1-007
 
KCNT1-010
 
KCNT1-201
 
KCNT1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNT1-001 ENSP00000417851
ENST00000487664
G5E9V0
Show all »
Show » Show » 1211 137 No 7
KCNT1-002 ENSP00000360822
ENST00000371757
Q5JUK3
Show all »
Show » Show » 1235 139.7 No 8
KCNT1-003 ENSP00000418777
ENST00000460750
F8WC49
Show all »
122 13.9 No 0
KCNT1-004 ENSP00000419086
ENST00000491806
C9JYL2
Show all »
Show » Show » 1221 137.4 No 8
KCNT1-005 ENSP00000419007
ENST00000488444
C9JZ51
Show all »
Show » Show » 1235 138.9 No 8
KCNT1-006 ENSP00000418003
ENST00000490355
C9JAX7
Show all »
Show » Show » 1234 138.9 No 8
KCNT1-007 ENSP00000417578
ENST00000486577
C9J9Y7
Show all »
Show » Show » 1213 137.6 No 8
KCNT1-010 ENSP00000420764
ENST00000473941
C9JBV2
Show all »
Show » 285 33.2 No 6
KCNT1-201 ENSP00000263604
ENST00000263604
Q5JUK3
Show all »
Show » Show » 1230 138.3 No 8
KCNT1-202 ENSP00000298480
ENST00000298480
Q5JUK3
Show all »
Show » Show » 1256 142 No 8