CREB3

GENE INFORMATION

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Gene name

CREB3 (HGNC Symbol)

Synonyms

Luman, LZIP

Description

cAMP responsive element binding protein 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]

Chromosome

9 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

35732332 - 35737001

Ensembl

ENSG00000107175 (version 73.37)

Entrez gene

10488

UniProt

O43889 (UniProt - Evidence at protein level)

neXtProt

NX_O43889

Antibodypedia

CREB3 antibodies
 

PROTEIN VIEW

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CREB3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CREB3-001 ENSP00000342136
ENST00000353704
O43889
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