EDF1

GENERAL INFORMATION

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Gene name

EDF1

Gene description

Endothelial differentiation-related factor 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues displayed moderate cytoplasmic positivity with additional nuclear staining in several cases. Squamous epithelium, exocrine pancreas and neuronal cells were strongly stained. Glial cells and myocytes were weakly stained or negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA035642
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

EDF1 (HGNC Symbol)

Synonyms

EDF-1

Description

Endothelial differentiation-related factor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that may regulate endothelial cell differentiation, lipid metabolism, and hormone-induced cardiomyocyte hypertrophy. The encoded protein has also been found to act as a transcriptional coactivator by interconnecting the general transcription factor TATA element-binding protein (TBP) and gene-specific activators. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

9

Cytoband

q34.3

Chromosome location (bp)

136862119 - 136866286

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107223 (version 78.38)

Entrez gene

8721

UniProt

O60869 (UniProt - Evidence at protein level)

neXtProt

NX_O60869

Antibodypedia

EDF1 antibodies


PROTEIN BROWSER

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ENST00000224073
 
ENST00000371648
 
ENST00000371649
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EDF1-001 ENSP00000224073
ENST00000224073
O60869
Show all »
Show » Show » 148 16.4 No 0
EDF1-002 ENSP00000360711
ENST00000371648
O60869
Show all »
Show » Show » 139 15.5 No 0
EDF1-003 ENSP00000360712
ENST00000371649
O60869
Show all »
Show » Show » 141 15.6 No 0