ABCA2

GENE INFORMATION

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Gene name

ABCA2 (HGNC Symbol)

Synonyms

ABC2

Description

ATP-binding cassette, sub-family A (ABC1), member 2 (HGNC Symbol)

Entrez gene summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q34.3

Chromosome location (bp)

139901686 - 139923367

Ensembl

ENSG00000107331 (version 73.37)

Entrez gene

20

UniProt

Q9BZC7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZC7

Antibodypedia

ABCA2 antibodies
 

PROTEIN VIEW

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 « 
 
ABCA2-001
 
ABCA2-002
 
ABCA2-005
 
ABCA2-009
 
ABCA2-013
 
ABCA2-014
 
ABCA2-016
 
ABCA2-019
 
ABCA2-022
 
ABCA2-201
 
ABCA2-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCA2-001 ENSP00000417701
ENST00000464876
F8WBD2
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Show » 56 6.7 No 1
ABCA2-002 ENSP00000344155
ENST00000341511
Q9BZC7
Show all »
Show » Show » 2436 270 No >9
ABCA2-005 ENSP00000406741
ENST00000448336
Q5SPZ6
Show all »
184 20.8 No 0
ABCA2-009 ENSP00000420084
ENST00000479446
Show » Show » 1441 159.9 No >9
ABCA2-013 ENSP00000420527
ENST00000459850
E7EU84
Show all »
Show » Show » 2024 223.1 No >9
ABCA2-014 ENSP00000419850
ENST00000488535
H0Y8C9
Show all »
Show » Show » 1066 118.1 No 6
ABCA2-016 ENSP00000418662
ENST00000487109
E9PGB2
Show all »
Show » 989 108.4 No 8
ABCA2-019 ENSP00000420289
ENST00000470535
196 21.6 No 0
ABCA2-022 ENSP00000420360
ENST00000490486
H0Y8E3
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195 21.9 No 0
ABCA2-201 ENSP00000265662
ENST00000265662
J3QSS3
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Show » Show » 2436 270 No >9
ABCA2-202 ENSP00000360666
ENST00000371605
Q9BZC7
Show all »
Show » Show » 2435 269.9 No >9