DDX50

GENE INFORMATION

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Gene name

DDX50 (HGNC Symbol)

Synonyms

GU2, GUB, MGC3199, RH-II/GuB

Description

DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 (HGNC Symbol)

Entrez gene summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. This gene and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. This gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

70661034 - 70706603

Ensembl

ENSG00000107625 (version 73.37)

Entrez gene

79009

UniProt

Q9BQ39 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BQ39

Antibodypedia

DDX50 antibodies
 

PROTEIN VIEW

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DDX50-001
 
DDX50-002
 
DDX50-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DDX50-001 ENSP00000362687
ENST00000373585
Q9BQ39
Show all »
Show » Show » 737 82.6 No 0
DDX50-002 ENSP00000474314
ENST00000471475
51 5.8 No 0
DDX50-003 ENSP00000474785
ENST00000483593
39 4.5 No 0