SMC3

GENE INFORMATION

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Gene name

SMC3 (HGNC Symbol)

Synonyms

BAM, bamacan, CSPG6, HCAP, SMC3L1

Description

structural maintenance of chromosomes 3 (HGNC Symbol)

Entrez gene summary

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q25.2

Chromosome location (bp)

112327449 - 112364394

Ensembl

ENSG00000108055 (version 73.37)

Entrez gene

9126

UniProt

Q9UQE7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UQE7

Antibodypedia

SMC3 antibodies
 

PROTEIN VIEW

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SMC3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMC3-001 ENSP00000354720
ENST00000361804
Q9UQE7
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