AATF

GENE INFORMATION

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Gene name

AATF (HGNC Symbol)

Synonyms

CHE-1, CHE1, DED

Description

apoptosis antagonizing transcription factor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

35306175 - 35414171

Ensembl

ENSG00000108270 (version 73.37)

Entrez gene

26574

UniProt

Q9NY61 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NY61

Antibodypedia

AATF antibodies
 

PROTEIN VIEW

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AATF-001
 
AATF-005
 
AATF-006
 
AATF-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AATF-001 ENSP00000225402
ENST00000225402
Q9NY61
Show all »
Show » 560 63.1 No 0
AATF-005 ENSP00000466918
ENST00000592751
K7ENE9
Show all »
55 6 No 0
AATF-006 ENSP00000468195
ENST00000589579
K7ERC2
Show all »
Show » 154 17.8 No 0
AATF-007 ENSP00000465512
ENST00000593084
Show » 98 11.3 No 0