ASPA

GENE INFORMATION

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Gene name

ASPA (HGNC Symbol)

Synonyms

ACY2, ASP

Description

aspartoacylase (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white matter. This protein is an NAA scavenger in other tissues. Mutations in this gene cause Canavan disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

3375668 - 3406713

Ensembl

ENSG00000108381 (version 73.37)

Entrez gene

443

UniProt

P45381 (UniProt - Evidence at protein level)

neXtProt

NX_P45381

Antibodypedia

ASPA antibodies
 

PROTEIN VIEW

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ASPA-001
 
ASPA-002
 
ASPA-003
 
ASPA-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ASPA-001 ENSP00000263080
ENST00000263080
P45381
Show all »
Show » Show » 313 35.7 No 0
ASPA-002 ENSP00000409976
ENST00000456349
P45381
Show all »
Show » Show » 313 35.7 No 0
ASPA-003 ENSP00000458324
ENST00000577034
I3L0T3
Show all »
Show » 79 8.9 No 0
ASPA-004 ENSP00000461358
ENST00000571278
I3L4M0
Show all »
Show » 56 6.3 No 0