CHRNE

GENE INFORMATION

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Gene name

CHRNE (HGNC Symbol)

Synonyms

ACHRE

Description

cholinergic receptor, nicotinic, epsilon (muscle) (HGNC Symbol)

Entrez gene summary

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]

Chromosome

17 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

4801069 - 4806369

Ensembl

ENSG00000108556 (version 73.37)

Entrez gene

1145

UniProt

Q04844 (UniProt - Evidence at protein level)

neXtProt

NX_Q04844

Antibodypedia

CHRNE antibodies
 

PROTEIN VIEW

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CHRNE-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHRNE-001 ENSP00000293780
ENST00000293780
Q04844
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