BLMH

GENE INFORMATION

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Gene name

BLMH (HGNC Symbol)

Synonyms

BH

Description

bleomycin hydrolase (HGNC Symbol)

Entrez gene summary

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

28575218 - 28619074

Ensembl

ENSG00000108578 (version 73.37)

Entrez gene

642

UniProt

Q13867 (UniProt - Evidence at protein level)

neXtProt

NX_Q13867

Antibodypedia

BLMH antibodies
 

PROTEIN VIEW

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BLMH-001
 
BLMH-002
 
BLMH-005
 
BLMH-006
 
BLMH-008
 
BLMH-009
 
BLMH-010
 
BLMH-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BLMH-001 ENSP00000261714
ENST00000261714
Q13867
Show all »
Show » Show » 455 52.6 No 0
BLMH-002 ENSP00000462353
ENST00000578090
J3KS79
Show all »
Show » 71 7.7 No 0
BLMH-005 ENSP00000462442
ENST00000581037
J3KSD8
Show all »
Show » 263 30.4 No 0
BLMH-006 ENSP00000468681
ENST00000577623
K7ESE8
Show all »
Show » 231 26.7 No 0
BLMH-008 ENSP00000466948
ENST00000577290
K7ENH5
Show all »
Show » 93 10.2 No 0
BLMH-009 ENSP00000466527
ENST00000580709
K7EMJ3
Show all »
Show » 67 8.1 No 0
BLMH-010 ENSP00000468486
ENST00000584603
K7ES02
Show all »
Show » 318 37.2 No 0
BLMH-201 ENSP00000378296
ENST00000394819
E7EMN3
Show all »
Show » 368 42.5 No 0