ALDH3A1

GENE INFORMATION

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Gene name

ALDH3A1 (HGNC Symbol)

Synonyms

ALDH3

Description

aldehyde dehydrogenase 3 family, member A1 (HGNC Symbol)

Entrez gene summary

Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008]

Chromosome

17 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

19641297 - 19652256

Ensembl

ENSG00000108602 (version 73.37)

Entrez gene

218

UniProt

P30838 (UniProt - Evidence at protein level)

neXtProt

NX_P30838

Antibodypedia

ALDH3A1 antibodies
 

PROTEIN VIEW

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 « 
 
ALDH3A1-001
 
ALDH3A1-005
 
ALDH3A1-006
 
ALDH3A1-007
 
ALDH3A1-009
 
ALDH3A1-010
 
ALDH3A1-013
 
ALDH3A1-014
 
ALDH3A1-016
 
ALDH3A1-018
 
ALDH3A1-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALDH3A1-001 ENSP00000225740
ENST00000225740
P30838
Show all »
Show » Show » 453 50.4 No 0
ALDH3A1-005 ENSP00000460482
ENST00000494157
I3L3I9
Show all »
Show » Show » 380 41.9 No 0
ALDH3A1-006 ENSP00000434685
ENST00000468746
E9PNN6
Show all »
Show » Show » 396 44.2 No 0
ALDH3A1-007 ENSP00000378923
ENST00000395555
A8MYB8
Show all »
Show » Show » 389 43.3 No 0
ALDH3A1-009 ENSP00000389766
ENST00000439102
C9JMC5
Show all »
Show » Show » 372 41.6 No 0
ALDH3A1-010 ENSP00000411821
ENST00000457500
P30838
Show all »
Show » Show » 453 50.4 No 0
ALDH3A1-013 ENSP00000458841
ENST00000574162
I3L1H6
Show all »
Show » Show » 131 15 No 0
ALDH3A1-014 ENSP00000460792
ENST00000570414
I3L3W9
Show all »
Show » 74 8.7 No 0
ALDH3A1-016 ENSP00000461189
ENST00000573368
I3L4E5
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Show » Show » 120 14 No 0
ALDH3A1-018 ENSP00000388369
ENST00000426645
C9JKT2
Show all »
Show » Show » 259 29.1 No 0
ALDH3A1-201 ENSP00000388469
ENST00000444455
P30838
Show all »
Show » Show » 453 50.4 No 0