ABI3

GENE INFORMATION

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Gene name

ABI3 (HGNC Symbol)

Synonyms

NESH, SSH3BP3

Description

ABI family, member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

17 (Chromosome progress)

Cytoband

q21.32

Chromosome location (bp)

47287589 - 47300587

Ensembl

ENSG00000108798 (version 73.37)

Entrez gene

51225

UniProt

Q9P2A4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9P2A4

Antibodypedia

ABI3 antibodies
 

PROTEIN VIEW

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ABI3-001
 
ABI3-002
 
ABI3-003
 
ABI3-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABI3-001 ENSP00000225941
ENST00000225941
Q9P2A4
Show all »
Show » Show » 366 39 No 0
ABI3-002 ENSP00000406651
ENST00000419580
Q9P2A4
Show all »
Show » Show » 360 38.4 No 0
ABI3-003 ENSP00000460776
ENST00000573347
160 16.1 No 0
ABI3-004 ENSP00000459171
ENST00000571035
Show » Show » 191 19.9 No 0