ABCC3

GENE INFORMATION

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Gene name

ABCC3 (HGNC Symbol)

Synonyms

cMOAT2, EST90757, MLP2, MOAT-D, MRP3

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q21.33

Chromosome location (bp)

48712138 - 48769613

Ensembl

ENSG00000108846 (version 73.37)

Entrez gene

8714

UniProt

O15438 (UniProt - Evidence at protein level)

neXtProt

NX_O15438

Antibodypedia

ABCC3 antibodies
 

PROTEIN VIEW

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ABCC3-001
 
ABCC3-002
 
ABCC3-003
 
ABCC3-004
 
ABCC3-006
 
ABCC3-007
 
ABCC3-008
 
ABCC3-011
 
ABCC3-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC3-001 ENSP00000285238
ENST00000285238
O15438
Show all »
Show » Show » 1527 169.3 No >9
ABCC3-002 ENSP00000395160
ENST00000427699
O15438
Show all »
Show » Show » 572 64.6 No >9
ABCC3-003 ENSP00000427073
ENST00000502426
O15438
Show all »
Show » Show » 510 55.3 No 5
ABCC3-004 ENSP00000427521
ENST00000505699
O15438
Show all »
Show » Show » 1238 137.3 No >9
ABCC3-006 ENSP00000422786
ENST00000515707
D6RAB7
Show all »
76 8.2 No 0
ABCC3-007 ENSP00000425697
ENST00000513511
D6RJE5
Show all »
43 4.6 No 0
ABCC3-008 ENSP00000424981
ENST00000515585
43 4.9 No 0
ABCC3-011 ENSP00000422058
ENST00000510633
H0Y8T5
Show all »
Show » 56 6.2 No 0
ABCC3-013 ENSP00000421755
ENST00000513745
Show » Show » 300 32.8 No 2