MPP2

GENERAL INFORMATION

? »

Gene name

MPP2

Gene description

Membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

19
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (cerebral cortex, testis)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in a few tissues, highest in a subset of neurons in CNS.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA026486
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

? »

Gene name

MPP2 (HGNC Symbol)

Synonyms

DKFZp761D0712, DLG2

Description

Membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) (HGNC Symbol)

Entrez gene summary

Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

43875357 - 43909711

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108852 (version 78.38)

Entrez gene

4355

UniProt

Q14168 (UniProt - Evidence at protein level)

neXtProt

NX_Q14168

Antibodypedia

MPP2 antibodies


PROTEIN BROWSER

? »
 
 
 « 
 
ENST00000269095
 
ENST00000377184
 
ENST00000461854
 
ENST00000473246
 
ENST00000518478
 
ENST00000518766
 
ENST00000520241
 
ENST00000520305
 
ENST00000520406
 
ENST00000521178
 
ENST00000522172
 
ENST00000523220
 
ENST00000523501
 
ENST00000523762
 
ENST00000523934
 
ENST00000524294
 
ENST00000536246
 
ENST00000612133
 
ENST00000622681
 
 » 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MPP2-001 ENSP00000269095
ENST00000269095
D3DX48
Show all »
Show » Show » 552 61.6 No 0
MPP2-002 ENSP00000366389
ENST00000377184
B4DZ84
Show all »
Show » Show » 569 63.3 No 0
MPP2-003 ENSP00000428286
ENST00000461854
D3DX49
Show all »
Show » Show » 576 64.6 No 0
MPP2-004 ENSP00000479767
ENST00000473246
Show » Show » 186 20.1 No 0
MPP2-005 ENSP00000428182
ENST00000518766
Q14168
Show all »
Show » Show » 597 66.8 No 0
MPP2-006 ENSP00000428468
ENST00000523220
Show » Show » 190 20.6 No 0
MPP2-007 ENSP00000430540
ENST00000523501
B4DZ84
Show all »
Show » Show » 541 60.5 No 0
MPP2-008 ENSP00000428136
ENST00000520305
Q14168
Show all »
Show » Show » 413 46.5 No 0
MPP2-011 ENSP00000428218
ENST00000523762
Show » Show » 140 15.3 No 0
MPP2-012 ENSP00000428938
ENST00000520241
E5RIM9
Show all »
Show » Show » 144 15.6 No 0
MPP2-013 ENSP00000430443
ENST00000521178
E5RFN8
Show all »
Show » Show » 126 13.7 No 0
MPP2-014 ENSP00000430349
ENST00000522172
E5RFN8
Show all »
Show » Show » 73 7.9 No 0
MPP2-015 ENSP00000429364
ENST00000518478
E5RIM9
Show all »
Show » 31 3.1 No 0
MPP2-016 ENSP00000428354
ENST00000520406
E5RFN8
Show all »
Show » Show » 151 16.4 No 0
MPP2-017 ENSP00000430797
ENST00000523934
E5RFN8
Show all »
Show » Show » 148 16 No 0
MPP2-018 ENSP00000483278
ENST00000524294
E5RFN8
Show all »
Show » Show » 112 12.2 No 0
MPP2-201 ENSP00000438012
ENST00000536246
B4DZ84
Show all »
Show » Show » 541 60.5 No 0
MPP2-202 ENSP00000478528
ENST00000612133
D3DX48
Show all »
Show » Show » 552 61.6 No 0
MPP2-203 ENSP00000480071
ENST00000622681
B4DZ84
Show all »
Show » Show » 541 60.5 No 0