ELF2

TISSUE ATLAS

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Gene description

E74-like factor 2 (ets domain transcription factor)

RNA tissue category

Expressed in all.

Protein summary

Detected at High or Medium expression level in 55 of 77 analyzed normal tissue cell types.

Protein expression

Moderate to strong nuclear staining in most normal tissues and cells. Surface epithelia showed strong nuclear immunoreactivity. Kupfer cells in liver sinusoids and alveolar macrophages displayed also strong positivity. Additional cytoplasmic staining in a few tissues e.g. trophoblasts in placenta, tubuli cells in kidney and gastric pits in stomach. In heart muscle, distinct staining of intercalated discs was observed.

Protein class

Transcription factors

Protein evidence

High

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Placenta
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

100
50
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA006057