CPE

GENE INFORMATION

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Gene name

CPE

Synonyms

Description

carboxypeptidase E (HGNC Symbol)

Entrez gene summary

This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q32.3

Chromosome location (bp)

166282346 - 166419472

Ensembl

ENSG00000109472 (version 73.37)

Entrez gene

1363

UniProt

P16870 (UniProt - Evidence at protein level)

neXtProt

NX_P16870

Antibodypedia

CPE antibodies
 

PROTEIN VIEW

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CPE-001
 
CPE-002
 
CPE-005
 
CPE-006
 
CPE-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CPE-001 ENSP00000386104
ENST00000402744
P16870
Show all »
Show » Show » 476 53.2 Yes 0
CPE-002 ENSP00000416601
ENST00000431967
C9JE88
Show all »
Show » 147 16.6 No 0
CPE-005 ENSP00000427629
ENST00000480404
Show » 108 11.9 No 0
CPE-006 ENSP00000424830
ENST00000513982
D6RF88
Show all »
Show » 139 15.7 No 0
CPE-007 ENSP00000423699
ENST00000511992
D6R930
Show all »
Show » 157 17.7 No 0