AADAT

GENE INFORMATION

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Gene name

AADAT (HGNC Symbol)

Synonyms

KAT2, KATII

Description

aminoadipate aminotransferase (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q33

Chromosome location (bp)

170981373 - 171012850

Ensembl

ENSG00000109576 (version 73.37)

Entrez gene

51166

UniProt

Q8N5Z0 (UniProt - Evidence at protein level)

neXtProt

NX_Q8N5Z0

Antibodypedia

AADAT antibodies
 

PROTEIN VIEW

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AADAT-001
 
AADAT-002
 
AADAT-003
 
AADAT-004
 
AADAT-005
 
AADAT-006
 
AADAT-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AADAT-001 ENSP00000423341
ENST00000515480
Q8N5Z0
Show all »
Show » Show » 425 47.4 No 0
AADAT-002 ENSP00000423190
ENST00000509167
Q8N5Z0
Show all »
Show » Show » 429 47.8 No 0
AADAT-003 ENSP00000226840
ENST00000353187
Q8N5Z0
Show all »
Show » Show » 425 47.4 No 0
AADAT-004 ENSP00000336808
ENST00000337664
Q8N5Z0
Show all »
Show » Show » 425 47.4 No 0
AADAT-005 ENSP00000423843
ENST00000502392
D6RC56
Show all »
Show » 180 19.7 No 0
AADAT-006 ENSP00000421389
ENST00000507375
D6RFY7
Show all »
Show » 209 22.8 No 0
AADAT-007 ENSP00000425067
ENST00000510340
D6REB9
Show all »
Show » 220 24.4 No 0