CLNK

GENE INFORMATION

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Gene name

CLNK (HGNC Symbol)

Synonyms

MIST

Description

cytokine-dependent hematopoietic cell linker (HGNC Symbol)

Entrez gene summary

MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).[supplied by OMIM, Mar 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p16.1

Chromosome location (bp)

10488019 - 10686489

Ensembl

ENSG00000109684 (version 73.37)

Entrez gene

116449

UniProt

Q7Z7G1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q7Z7G1

Antibodypedia

CLNK antibodies
 

PROTEIN VIEW

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CLNK-001
 
CLNK-002
 
CLNK-003
 
CLNK-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLNK-001 ENSP00000226951
ENST00000226951
Q7Z7G1
Show all »
Show » Show » 428 49.6 No 0
CLNK-002 ENSP00000427208
ENST00000507719
Q7Z7G1
Show all »
Show » 169 19.4 No 0
CLNK-003 ENSP00000427256
ENST00000515667
D6RJB9
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Show » Show » 166 19.5 No 0
CLNK-201 ENSP00000390744
ENST00000442825
Q7Z7G1
Show all »
Show » 169 19.4 No 0