Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Vesicles

Additional location(s)

Nucleus but not nucleoli 

Staining summary

Mainly localized to vesicles. In addition localized to the nucleus.

Reliability (APE)

Low

Antibodies in assay

HPA035671, HPA035672
 

Antibody HPA035671

 

Antibody HPA035672

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Vesicles  

Staining characteristics

  

Staining intensity

Strong Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Vesicles  

Staining characteristics

  

Staining intensity

Moderate Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-251 MG

Toggle channels

 
 

Location(s)

Nucleus but not nucleoli, Vesicles  

Staining characteristics

  

Staining intensity

Weak Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in vesicles.
 

Immunofluorescent staining of human cell line U-2 OS shows no positivity.
 

Summary

Staining of vesicles in all three cell lines with additional staining of nucleus in U-251 MG and U-2 OS.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Nucleus but not nucleoli
Endosome