P2RX3

TISSUE ATLAS

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Gene description

Purinergic receptor P2X, ligand-gated ion channel, 3

RNA tissue category

Group enriched (heart muscle, stomach, testis).

Protein summary

Detected at Medium expression level in 8 of 81 analyzed normal tissue cell types.

Protein expression

Gall bladder, renal tubules, glandular cells of breast, squamous epithelium of tonsil and glandular cells of cervix showed moderate cytoplasmic and/or nuclear positivity. Strong membranous positivity was observed in exocrine glandular cells in pancreas. Remaining normal tissues were weakly stained or negative.

Protein class

Potential transmembrane proteins, Transporters

Protein evidence

Low

Protein reliability

Uncertain based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Hippocampus
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

20
10
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

HPA057776