CPT1A

GENE INFORMATION

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Gene name

CPT1A (HGNC Symbol)

Synonyms

CPT1, CPT1-L, L-CPT1

Description

carnitine palmitoyltransferase 1A (liver) (HGNC Symbol)

Entrez gene summary

The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

68522088 - 68611878

Ensembl

ENSG00000110090 (version 73.37)

Entrez gene

1374

UniProt

P50416 (UniProt - Evidence at protein level)

neXtProt

NX_P50416

Antibodypedia

CPT1A antibodies
 

PROTEIN VIEW

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CPT1A-001
 
CPT1A-002
 
CPT1A-004
 
CPT1A-006
 
CPT1A-007
 
CPT1A-008
 
CPT1A-009
 
CPT1A-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CPT1A-001 ENSP00000439084
ENST00000540367
P50416
Show all »
Show » Show » 756 86.2 No 2
CPT1A-002 ENSP00000446108
ENST00000539743
P50416
Show all »
Show » Show » 773 88.4 No 2
CPT1A-004 ENSP00000454332
ENST00000538994
H3BMD2
Show all »
Show » Show » 78 9 No 0
CPT1A-006 ENSP00000265641
ENST00000265641
P50416
Show all »
Show » Show » 773 88.4 No 2
CPT1A-007 ENSP00000457663
ENST00000561996
H3BUJ0
Show all »
Show » Show » 93 10.4 No 1
CPT1A-008 ENSP00000455116
ENST00000569129
H3BP22
Show all »
Show » Show » 118 12.9 No 1
CPT1A-009 ENSP00000457826
ENST00000565318
H3BUV7
Show all »
Show » Show » 134 14.8 No 2
CPT1A-201 ENSP00000365803
ENST00000376618
P50416
Show all »
Show » Show » 756 86.2 No 2