APOC3

GENE INFORMATION

? »

Gene name

APOC3

Synonyms

Description

apolipoprotein C-III (HGNC Symbol)

Entrez gene summary

Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

116700422 - 116703788

Ensembl

ENSG00000110245 (version 73.37)

Entrez gene

345

UniProt

P02656 (UniProt - Evidence at protein level)

neXtProt

NX_P02656

Antibodypedia

APOC3 antibodies
 

PROTEIN VIEW

? »
 
 
 
APOC3-001
 
APOC3-002
 
APOC3-003
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APOC3-001 ENSP00000227667
ENST00000227667
P02656
Show all »
Show » Show » 99 10.9 Yes 0
APOC3-002 ENSP00000410614
ENST00000433777
C9J2Q0
Show all »
Show » 55 5.9 Yes 0
APOC3-003 ENSP00000364494
ENST00000375345
B0YIW2
Show all »
Show » Show » 117 12.8 Yes 0