CARS

GENE INFORMATION

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Gene name

CARS (HGNC Symbol)

Synonyms

CARS1

Description

cysteinyl-tRNA synthetase (HGNC Symbol)

Entrez gene summary

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2010]

Chromosome

11 (Chromosome progress)

Cytoband

p15.4

Chromosome location (bp)

3022152 - 3078843

Ensembl

ENSG00000110619 (version 73.37)

Entrez gene

833

UniProt

P49589 (UniProt - Evidence at protein level)

neXtProt

NX_P49589

Antibodypedia

CARS antibodies
 

PROTEIN VIEW

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CARS-001
 
CARS-002
 
CARS-003
 
CARS-004
 
CARS-007
 
CARS-012
 
CARS-016
 
CARS-201
 
CARS-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CARS-001 ENSP00000380300
ENST00000397111
P49589
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Show » Show » 748 85.5 No 0
CARS-002 ENSP00000278224
ENST00000278224
P49589
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Show » Show » 726 82.8 No 0
CARS-003 ENSP00000431368
ENST00000531387
E9PLP0
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Show » 128 14.3 No 0
CARS-004 ENSP00000369897
ENST00000380525
P49589
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Show » Show » 831 94.6 No 0
CARS-007 ENSP00000408802
ENST00000439280
C9JLN0
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Show » 45 5.1 No 0
CARS-012 ENSP00000434184
ENST00000527330
E9PRS8
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Show » 76 8.4 No 0
CARS-016 ENSP00000432619
ENST00000529772
E9PPK8
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Show » 83 9.2 No 0
CARS-201 ENSP00000380303
ENST00000397114
A8MVQ3
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Show » Show » 738 84.5 No 0
CARS-202 ENSP00000384069
ENST00000401769
B4DKY1
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Show » Show » 739 84.3 No 0