CD81

GENE INFORMATION

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Gene name

CD81 (HGNC Symbol)

Synonyms

TAPA-1, TAPA1, TSPAN28

Description

CD81 molecule (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

2397407 - 2418649

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110651 (version 75.37)

Entrez gene

975

UniProt

P60033 (UniProt - Evidence at protein level)

neXtProt

NX_P60033

Antibodypedia

CD81 antibodies
 

PROTEIN VIEW

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 « 
 
CD81-001
 
CD81-002
 
CD81-003
 
CD81-004
 
CD81-005
 
CD81-006
 
CD81-007
 
CD81-012
 
CD81-013
 
CD81-014
 
CD81-015
 
CD81-017
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD81-001 ENSP00000263645
ENST00000263645
P60033
Show all »
Show » Show » 236 25.8 No 4
CD81-002 ENSP00000433178
ENST00000475945
E9PM31
Show all »
Show » Show » 93 10.1 No 1
CD81-003 ENSP00000437242
ENST00000492627
E9PJK1
Show all »
Show » Show » 165 18 No 2
CD81-004 ENSP00000432497
ENST00000493525
E9PQV4
Show all »
Show » Show » 99 10.7 No 3
CD81-005 ENSP00000370424
ENST00000381036
A6NMH8
Show all »
Show » Show » 274 29.8 Yes 4
CD81-006 ENSP00000432249
ENST00000492252
E9PRJ8
Show all »
Show » Show » 209 22.5 No 4
CD81-007 ENSP00000432033
ENST00000481687
E9PIF1
Show all »
Show » Show » 242 25.9 No 3
CD81-012 ENSP00000432723
ENST00000530648
E9PPF5
Show all »
Show » Show » 52 5.7 No 1
CD81-013 ENSP00000435633
ENST00000533417
H0YEE2
Show all »
Show » Show » 148 16 No 3
CD81-014 ENSP00000433767
ENST00000527343
H0YDJ9
Show all »
Show » Show » 225 24.4 No 4
CD81-015 ENSP00000433904
ENST00000464784
E9PM31
Show all »
Show » Show » 221 23.7 No 4
CD81-017 ENSP00000431780
ENST00000526072
E9PJK1
Show all »
Show » Show » 165 18 No 2