PPFIBP1

GENE INFORMATION

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Gene name

PPFIBP1 (HGNC Symbol)

Synonyms

hSGT2, hSgt2p, L2, SGT2

Description

PTPRF interacting protein, binding protein 1 (liprin beta 1) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

p11.22

Chromosome location (bp)

27676364 - 27848497

Ensembl

ENSG00000110841 (version 73.37)

Entrez gene

8496

UniProt

Q86W92 (UniProt - Evidence at protein level)

neXtProt

NX_Q86W92

Antibodypedia

PPFIBP1 antibodies
 

PROTEIN VIEW

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 « 
 
PPFIBP1-001
 
PPFIBP1-002
 
PPFIBP1-003
 
PPFIBP1-004
 
PPFIBP1-005
 
PPFIBP1-006
 
PPFIBP1-007
 
PPFIBP1-008
 
PPFIBP1-009
 
PPFIBP1-010
 
PPFIBP1-012
 
PPFIBP1-015
 
PPFIBP1-016
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPFIBP1-001 ENSP00000228425
ENST00000228425
Q86W92
Show all »
Show » 1005 113.2 No 0
PPFIBP1-002 ENSP00000444304
ENST00000540114
F5GZP6
Show all »
Show » 744 84.1 No 0
PPFIBP1-003 ENSP00000445425
ENST00000537927
Q86W92
Show all »
Show » 858 97 No 0
PPFIBP1-004 ENSP00000445822
ENST00000545381
F5H6Q7
Show all »
Show » 281 32.2 No 0
PPFIBP1-005 ENSP00000438036
ENST00000545334
F5H0E0
Show all »
109 12 No 0
PPFIBP1-006 ENSP00000444046
ENST00000535047
Q86W92
Show all »
Show » 170 19 No 0
PPFIBP1-007 ENSP00000314724
ENST00000318304
Q86W92
Show all »
Show » 1011 114 No 0
PPFIBP1-008 ENSP00000443442
ENST00000542629
Q86W92
Show all »
Show » 980 110.3 No 0
PPFIBP1-009 ENSP00000442462
ENST00000538433
18 2.1 No 0
PPFIBP1-010 ENSP00000437438
ENST00000535575
F5H6Q7
Show all »
86 9.4 No 0
PPFIBP1-012 ENSP00000438174
ENST00000539326
Show » 242 27.2 No 0
PPFIBP1-015 ENSP00000445132
ENST00000542187
F5H495
Show all »
152 16.9 No 0
PPFIBP1-016 ENSP00000443324
ENST00000537261
H0YGH8
Show all »
205 22.4 No 0