BCL7A

GENE INFORMATION

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Gene name

BCL7A (HGNC Symbol)

Synonyms

BCL7

Description

B-cell CLL/lymphoma 7A (HGNC Symbol)

Entrez gene summary

This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

q24.31

Chromosome location (bp)

122457328 - 122499948

Ensembl

ENSG00000110987 (version 73.37)

Entrez gene

605

UniProt

Q4VC05 (UniProt - Evidence at protein level)

neXtProt

NX_Q4VC05

Antibodypedia

BCL7A antibodies
 

PROTEIN VIEW

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BCL7A-001
 
BCL7A-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCL7A-001 ENSP00000445868
ENST00000538010
Q4VC05
Show all »
Show » Show » 231 25 No 0
BCL7A-002 ENSP00000261822
ENST00000261822
Q4VC05
Show all »
Show » Show » 210 22.8 No 0