TENC1

GENERAL INFORMATION

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Gene name

TENC1

Gene description

Tensin like C1 domain containing phosphatase (tensin 2)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Renal glomeruli displayed strong cytoplasmic and membranous positivity. Hepatocytes and gall bladder were moderately stained. Endothelial cells were distinctly stained. Remaining normal tissues were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA034659
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

TENC1 (HGNC Symbol)

Synonyms

C1-TEN, KIAA1075, TNS2

Description

Tensin like C1 domain containing phosphatase (tensin 2) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q13.13

Chromosome location (bp)

53046969 - 53064372

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111077 (version 78.38)

Entrez gene

23371

UniProt

Q63HR2 (UniProt - Evidence at protein level)

neXtProt

NX_Q63HR2

Antibodypedia

TENC1 antibodies


PROTEIN BROWSER

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ENST00000314250
 
ENST00000314276
 
ENST00000379902
 
ENST00000546602
 
ENST00000549700
 
ENST00000552570
 
ENST00000602335
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TENC1-001 ENSP00000369232
ENST00000379902
Q63HR2
Show all »
Show » Show » 1285 138.8 No 0
TENC1-002 ENSP00000319756
ENST00000314276
Q63HR2
Show all »
Show » Show » 1419 153.6 No 0
TENC1-003 ENSP00000319684
ENST00000314250
Q63HR2
Show all »
Show » Show » 1409 152.6 No 0
TENC1-008 ENSP00000449363
ENST00000546602
Q63HR2
Show all »
Show » Show » 1312 142.7 No 0
TENC1-010 ENSP00000447021
ENST00000552570
Q63HR2
Show all »
Show » Show » 1407 152.5 No 0
TENC1-017 ENSP00000449361
ENST00000549700
F8VV64
Show all »
Show » Show » 1344 146 No 0
TENC1-022 ENSP00000473388
ENST00000602335
Show » Show » 197 21.4 No 0